Redox Status and Proteostasis in Ageing and Disease
نویسندگان
چکیده
منابع مشابه
Redox Status and Proteostasis in Ageing and Disease
1Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, 43125 Parma, Italy 2Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, 15784 Athens, Greece 3Laboratory of Cell Signaling and Redox Biology, Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy 4Service of Endocrinolog...
متن کاملProteostasis and REDOX state in the heart.
Force-generating contractile cells of the myocardium must achieve and maintain their primary function as an efficient mechanical pump over the life span of the organism. Because only half of the cardiomyocytes can be replaced during the entire human life span, the maintenance strategy elicited by cardiac cells relies on uninterrupted renewal of their components, including proteins whose special...
متن کاملefl students gender and socioeconomic status: the use of politeness strategies in the first and second languages
within the components of communicative competence, a special emphasis is put on the “rules of politeness,” specifically the politeness strategies (brown and levinson, 1978) that speakers deploy when performing the request speech act. this is because the degree of imposition that making a request places upon one’s interlocutor(s) has been seen to be influenced by several factors among which, as ...
Epigenetic inheritance of proteostasis and ageing
Abundant evidence shows that the genome is not as static as once thought and that gene expression can be reversibly modulated by the environment. In some cases, these changes can be transmitted to the next generation even if the environment has reverted. Such transgenerational epigenetic inheritance requires that information be stored in the germline in response to exogenous stressors. One of t...
متن کاملHealthy ageing through regulated proteostasis.
During metazoan life, protein homeostasis (proteostasis) declines with age due to impaired proteasome activity. The signalling pathways activated by growth factors that regulate proteostasis and their importance to ageing are just emerging. In this issue, Liu et al report a crucial role of epidermal growth factor (EGF) in regulating Caenorhabditis elegans lifespan through the RAF/MAPK pathway. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2016
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2016/7476241